Organic letters

Novel Synthesis of 2-Aryl and 2, 3-Disubstituted Indoles by Modified Double Elimination Protocol

G Babu, A Orita, J Otera

Index: Babu, Govindarajulu; Orita, Akihiro; Otera, Junzo Organic Letters, 2005 , vol. 7, # 21 p. 4641 - 4643

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Citation Number: 20

Abstract

Syntheses of 2-aryl and 2, 3-substituted indoles were realized by modified double elimination protocol. Under basic conditions, vinyl sulfones derived from the reaction of 2- aminobenzyl sulfone with benzaldehydes underwent cyclization and alkylation followed by elimination of sulfinic acid to afford 2, 3-substituted indoles.

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