Synthetic Communications

Syntheses of some N-alkylmaleimides

ZY Wang

Index: Wang, Z. Y. Synthetic Communications, 1990 , vol. 20, # 11 p. 1607 - 1610

Full Text: HTML

Citation Number: 26

Abstract

The imidization of N-substituted rnaleamic acids in the presence of a dehydrating agent, such as acetic anhydride, to yield the N-substituted maleimides is a well-known classic reaction'. However, the reaction requires a large excess of acetic anhydride as both reagent and solvent and sodium acetate as a base, and is limited only to aryl substituents. In the case of primary alkyl groups, low to moderate yields (15- 60%) of N-alkyl maleimides were obtainedZ3. For ...

Related Articles:

Nickel-catalyzed coupling of isocyanates with 1, 3-iodoesters and halobenzenes: a novel method for the synthesis of imide and amide derivatives

[Hsieh, Jen-Chieh; Cheng, Chien-Hong Chemical Communications, 2005 , # 36 p. 4554 - 4556]

Syntheses of some N-alkylmaleimides

[Synthetic Communications, , vol. 20, # 11 p. 1607 - 1610]

An improved approach to N-substituted maleimides and phthalimides by microwave-promoted Mitsunobu reaction

[Mayer, Christoph D.; Kehrel, Marcus; Bracher, Franz Organic Preparations and Procedures International, 2008 , vol. 40, # 6 p. 574 - 574]

More Articles...