Acta Biologica Hungarica 1989-01-01

The antiallatal effects on locusts and lethal effects on nematodes of synthetic precocene-1 derivatives differing at the carbon 7 position.

A Fodor, P Deák, M Berényi, T Timár, S Hosztafi, I Kiss

Index: Acta Biol. Hung. 40(3) , 255-69, (1989)

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Abstract

Fourteen precocene-1 (P1) derivatives differing at C-7 were synthetized and tested for their antiallatal activities on Locusta migratoria (in vitro and in vivo) and nematocidal effects on Caenorhaditis elegans. An outstanding antiallatal effect was produced by 7-propargyloxy-P1 in vitro. It caused an elevated rate of mortality when applied in vivo to locusts or nematodes. The antiallatal effect of 7-cyclopentyloxy-P1 was not accompanied by toxicity. Aralkyloxy substitution at C-7 eliminated the precocene activity.

Related Compounds

  • 2H-1-Benzopyran,7...

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