Analytical chemistry 2015-08-18

Droplet spray ionization from a glass microscope slide: real-time monitoring of ethylene polymerization.

Jie Jiang, Hong Zhang, Ming Li, Maria T Dulay, Andrew J Ingram, Na Li, Hong You, Richard N Zare

Index: Anal. Chem. 87 , 8057-62, (2015)

Full Text: HTML

Abstract

Ambient ionization mass spectrometry is achieved in a simple manner by loading a sample solution onto a corner of a microscope cover glass positioned in front of the inlet to a mass spectrometer and applying a high voltage to the sample. The resulting stream of charged droplets is stable, has no contamination from the substrate platform, and can be used repeatedly. The utility of droplet spray for in situ analysis and real-time monitoring of chemical reactions was demonstrated by the bis(cyclopentadienyl)zirconium dichloride (zirconocene dichloride)/methylaluminoxane, Cp2ZrCl2/MAO, homogeneously catalyzed polymerization of ethylene in various solutions. Reaction times ranged from seconds to minutes, and catalytically active species and polymeric products of ethylene were acquired and identified by tandem mass spectrometry.

Related Compounds

  • Acetonitrile
  • Methanol
  • thf
  • Toluene
  • Fluorobenzene

Related Articles:

Neuroprotective effect of modified Chungsimyeolda-tang, a traditional Korean herbal formula, via autophagy induction in models of Parkinson's disease.

2015-01-15

[J. Ethnopharmacol. 159 , 93-101, (2014)]

Biomolecular imaging with a C60-SIMS/MALDI dual ion source hybrid mass spectrometer: instrumentation, matrix enhancement, and single cell analysis.

2014-11-01

[J. Am. Soc. Mass Spectrom. 25(11) , 1897-907, (2014)]

Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking.

2014-07-01

[Autophagy 10(7) , 1241-55, (2014)]

Diclofenac toxicity in human intestine ex vivo is not related to the formation of intestinal metabolites.

2015-01-01

[Arch. Toxicol. 89(1) , 107-19, (2015)]

Methionine oxidation accelerates the aggregation and enhances the neurotoxicity of the D178N variant of the human prion protein.

2014-12-01

[Biochim. Biophys. Acta 1842(12 Pt A) , 2345-56, (2014)]

More Articles...