Functionalization of 6-nitrobenzo[1,3]dioxole with carbonyl compounds via TDAE methodology.
Ouassila Amiri-Attou, Thierry Terme, Patrice Vanelle
Index: Molecules 10(3) , 545-51, (2005)
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Abstract
We report herein the synthesis of substituted 2-(6-nitrobenzo[1,3]dioxol-5-yl)-1- aryl ethanols and 2-(6-nitrobenzo[1,3]dioxol-5-yl)-propionic acid ethyl esters from the reaction of 5-chloromethyl-6-nitrobenzo[1,3]dioxole with various aromatic carbonyl and alpha- carbonyl ester derivatives using the tetrakis(dimethylamino)ethylene (TDAE) methodology.
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