Molecules 2005-01-01

Functionalization of 6-nitrobenzo[1,3]dioxole with carbonyl compounds via TDAE methodology.

Ouassila Amiri-Attou, Thierry Terme, Patrice Vanelle

Index: Molecules 10(3) , 545-51, (2005)

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Abstract

We report herein the synthesis of substituted 2-(6-nitrobenzo[1,3]dioxol-5-yl)-1- aryl ethanols and 2-(6-nitrobenzo[1,3]dioxol-5-yl)-propionic acid ethyl esters from the reaction of 5-chloromethyl-6-nitrobenzo[1,3]dioxole with various aromatic carbonyl and alpha- carbonyl ester derivatives using the tetrakis(dimethylamino)ethylene (TDAE) methodology.


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