Biomedical & environmental mass spectrometry 1987-09-01

Abnormal n-nonacosane storage in humans: detection by gas chromatography/mass spectrometry of tissue extracts.

F Rocchiccioli, A Lageron, C Duboucher

Index: Biomed. Environ. Mass Spectrom. 14(9) , 481-5, (1987)

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Abstract

We report a case of n-nonacosane storage disease, which went undiagnosed until the death of a 55-year-old farmer. Clinical, histological, and biochemical features are discussed. n-Nonacosane storage was identified by gas chromatographic-mass spectrometric analysis of different tissue extracts, n-nonacosane concentration reaching 1.2 mg g-1 of lung tissue and 0.32 mg g-1 of liver tissue. It was possible to rule out a work-induced intoxication, and n-nonacosane storage appeared to be accounted for by a lifelong, heavy consumption of unpeeled apples and Brussels sprouts.


Related Compounds

  • Nonacosane

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