Photoswitched cell adhesion on surfaces with RGD peptides

J Auernheimer, C Dahmen, U Hersel…

Index: Auernheimer, Joerg; Dahmen, Claudia; Hersel, Ulrich; Bausch, Andreas; Kessler, Horst Journal of the American Chemical Society, 2005 , vol. 127, # 46 p. 16107 - 16110

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Citation Number: 161

Abstract

Coating of surfaces by RGD peptides is well-known. Herein we describe the possibility to switch cell adhesion properties by changing the distance and orientation of the RGD peptides to the surface. A set of RGD peptides of the type cyclo (-RGDfK-) was synthesized containing the photoswitchable 4-[(4-aminophenyl) azo] benzocarbonyl central unit as spacer between the acrylamide anchor and the RGD peptide. PMMA (poly methyl ...