Synthesis of 1??Aryl??1H??indazoles via a Ligand??Free Copper??Catalyzed Intramolecular Amination Reaction
…, X Liu, X Wang, Q Cai, K Ding
Index: Gao, Mingshan; Liu, Xiujie; Wang, Xianyang; Cai, Qian; Ding, Ke Chinese Journal of Chemistry, 2011 , vol. 29, # 6 p. 1199 - 1204
Full Text: HTML
Citation Number: 10
Abstract
Abstract A general synthesis of 1-aryl-1-H-indazoles from o-halogenated aryl aldehydes or ketones and aryl hydrazines was described. This protocol included an intermolecular condensation and a ligand-free copper-catalyzed intramolecular Ullmann-type coupling reaction. This method was applied to a wide range of substrates to produce the indazole products in good yields.
Related Articles:
[Pabba, Chittari; Wang, Hong-Jun; Mulligan, Susan R.; Chen, Zhen-Jia; Stark, Todd M.; Gregg, Brian T. Tetrahedron Letters, 2005 , vol. 46, # 44 p. 7553 - 7557]
[Pabba, Chittari; Wang, Hong-Jun; Mulligan, Susan R.; Chen, Zhen-Jia; Stark, Todd M.; Gregg, Brian T. Tetrahedron Letters, 2005 , vol. 46, # 44 p. 7553 - 7557]