Canadian Journal of Chemistry

Reductions with Sulfurated Borohydrides. VI. The Reduction of Nitro, Nitrile, Amide, and Nitroso Groups

JM Lalancette, JR Brindle

Index: Lalancette,J.M.; Brindle,J.R. Canadian Journal of Chemistry, 1971 , vol. 49, p. 2990 - 2995

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Citation Number: 30

Abstract

Aromatic nitro compounds can be reduced with sulfurated sodium borohydride to the corresponding amine in high yields (≈ 80%) without affecting ester, nitrile, ether, halide or olefinic groups also present. With ortho-substituted nitro compounds the yields are around 60%. Primary aliphatic nitro compounds are reduced to the corresponding nitrile in high yields. Secondary aliphatic nitro compounds are reduced to mixtures of ketones and the ...

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