Steroids 1996-06-01

Synthesis of oxido-bridged analogs of 18-hydroxyprogesterone.

M O Doctorovich, A A Ghini, G Burton

Index: Steroids 61(6) , 345-8, (1996)

Full Text: HTML

Abstract

18-Hydroxy-6,19-oxidoprogesterone and 18-hydroxy-11, 19-oxidoprogesterone were synthesized from readily available materials. The functionalization of C-18 was accomplished with phenyliodosodiacetate/iodine, whereas that of C-19 was carried out with the mercuric oxide/iodine system, both under irradiation with visible light. For 18-hydroxy-11,19-oxidoprogesterone, C-19 was functionalized before C-18, whereas the reverse order had to be used for the 6,19-oxido derivative.

Related Compounds

  • mercuric oxide

Related Articles:

Cleavage of a model peptide at its glycine residue by alkaline mercuric oxycyanide.

1989-07-01

[Int. J. Pept. Protein Res. 34(1) , 52-5, (1989)]

Periorbital contact dermatitis due to yellow mercuric oxide.

1996-07-01

[Contact Dermatitis 35(1) , 61, (1996)]

Transformation of epiandrosterone into 3-oxa-, 3-thia-, 3-selena-, and 3-aza-17-oxaandrostanes of the 5 alpha series based on beta-scission of alkoxyl radicals.

1990-08-01

[Steroids 55(8) , 353-9, (1990)]

Investigation of an unexpected addition reaction that occurs when 2,3:4,5-di-O-isopropylidene-D-ribose diethyl dithioacetal is treated with mercuric oxide and mercuric chloride.

2001-06-15

[J. Org. Chem. 66(12) , 4405-8, (2001)]

Comparison of neurite outgrowth with neurofilament protein subunit levels in neuroblastoma cells following mercuric oxide exposure.

1995-05-01

[Clin. Exp. Pharmacol. Physiol. 22(5) , 362-3, (1995)]

More Articles...