Journal of Oleo Science 2008-01-01

Synthesis and physiological activity of thiophenes and furans with 3- and 4-methoxyacetophenone derivatives.

Shinya Tachibana, Takashi Gotou, Masato Nomura

Index: J. Oleo Sci. 57(2) , 107-13, (2008)

Full Text: HTML

Abstract

The synthesis and physiological activity of thiophenes and furans with methoxyacetophenone derivatives were examined. 3-Methoxyacetophenone (1) and 4-methoxyacetophenone (2) were converted, respectively, to the oximes (3) and (4) by oximation with hydroxylamine hydrochloride, and to the primary amines (5) and (6) by reduction with LiAlH(4). The primary amine derivatives were further converted into the thiophene and furan compounds (5a) approximately (5h) and (6a) approximately (6h), respectively. Bioassay of these compounds (5a) approximately (5h) and (6a) approximately (6h) on the germination of lettuce(Lactuca satiba) seeds showed that compound (5b) exhibits growthpromoting activity.

Related Compounds

  • Lithium Aluminium...
  • Acetanisole

Related Articles:

Ionic complex of risedronate with positively charged deoxycholic acid derivative: evaluation of physicochemical properties and enhancement of intestinal absorption in rats.

2014-12-01

[Arch. Pharm. Res. 37(12) , 1560-9, (2014)]

Heterolysis of Dihydrogen by Silver Alkoxides and Fluorides.

2015-07-06

[Chemistry 21 , 10160-9, (2015)]

Identifying erlotinib-sensitive non-small cell lung carcinoma tumors in mice using [(11)C]erlotinib PET.

2015-01-01

[EJNMMI Res. 5 , 4, (2015)]

Pro-toxic dehydropyrrolizidine alkaloids in the traditional Andean herbal medicine "asmachilca".

2015-08-22

[J. Ethnopharmacol. 172 , 179-94, (2015)]

Salts of highly fluorinated weakly coordinating anions as versatile precursors towards hydrogen storage materials.

2015-12-07

[Dalton Trans. 44 , 19469-77, (2015)]

More Articles...