Organic & Biomolecular Chemistry 2012-12-28

Potassium iodide catalyzed simultaneous C3-formylation and N-aminomethylation of indoles with 4-substituted-N,N-dimethylanilines.

Lan-Tao Li, Hong-Ying Li, Li-Juan Xing, Li-Juan Wen, Peng Wang, Bin Wang

Index: Org. Biomol. Chem. 10(48) , 9519-22, (2012)

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Abstract

A one-pot dual functionalization of indoles has been developed. The simultaneous C3-formylation and N-aminomethylation of indoles can be achieved using readily available potassium iodide as a catalyst and tert-butyl peroxybenzoate as a co-oxidant.

Related Compounds

  • Potassium iodide
  • N-Methylaniline
  • 4-TERT-BUTYL-...

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