Organic & Biomolecular Chemistry 2012-07-07

Synthesis and evaluation of atropos dihydro-5H-dibenzazepinium halide PTCs derived from α-methylbenzylamine.

Barry Lygo, Umar Butt, Maria Cormack

Index: Org. Biomol. Chem. 10(25) , 4968-76, (2012)

Full Text: HTML

Abstract

A short synthetic route to diastereoisomeric atropos dihydro-5H-dibenz[c,e]azepinium salts via reaction of a single enantiomer of (R)-α-methylbenzylamine with a racemic atropos biphenol derivative is described. Compounds prepared via this approach are used to provide strong evidence that structurally related tropos dihydro-5H-dibenz[c,e]azepinium salts preferentially react via a single conformation in PTC reactions involving glycine imine enolates.

Related Compounds

  • L-1-Phenylethylam...
  • (R)-(+)-1-Phenyle...
  • 1-Phenylethanamine

Related Articles:

Interactions of an asymmetric amine with a non-C2 symmetric Cu-salen complex: an EPR/ENDOR and HYSCORE investigation.

2011-12-07

[Phys. Chem. Chem. Phys. 13(45) , 20427-34, (2011)]

Synthesis, Crystal Structure, Absolute Configuration and Antitumor Activity of the Enantiomers of 5-Bromo-2-chloro-N-(1-phenylethyl)pyridine-3-sulfonamide.

2015-01-01

[Molecules 20 , 20926-38, (2015)]

Enantioselective nanofiber-spinning of chiral calixarene receptor with guest.

2007-08-28

[Chem. Commun. (Camb.) (32) , 3398-400, (2007)]

Characterization of free and immobilized (S)-aminotransferase for acetophenone production.

2007-09-01

[Appl. Microbiol. Biotechnol. 76(4) , 843-51, (2007)]

Chiral self-discrimination of the enantiomers of alpha-phenylethylamine derivatives in proton NMR.

2009-05-01

[Magn. Reson. Chem. 47(5) , 423-7, (2009)]

More Articles...