Nucleic Acids Symposium Series 1980-01-01

Further studies on oligoribonucleotide synthesis.

W T Markiewicz, E Biała, R W Adamiak, K Grześkowiak, R Kierzek, A Kraszewski, J Stawiński, M Wiewiórowski

Index: Nucleic Acids Symp. Ser. (7) , 115-27, (1980)

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Abstract

Recent results concerning the synthesis of oligoribonucleotides via the phosphotriester method, such as functionalization of ribonucleosides, new phosphorylating agents, 5'-O-sulfonylation and chromatography on Sephadex LH-20 for monitoring the removal of internucleotide phosphotriester groups, are presented. To show that efficiency of a new approach to the synthesis of oligoribonucleotides the pentamer /Up/4U was obtained.

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