Canadian journal of biochemistry 1979-10-01

N-acylation of tyramines: purification and characterization of an arylamine N-acetyltransferase from rat brain and liver.

P H Yu, A A Boulton

Index: Can. J. Biochem. 57(10) , 1204-9, (1979)

Full Text: HTML

Abstract

The N-acylation of tyramine isomers and other biogenic amines has been studied. The liver exhibits the highest activity towards tyramines, while the brain exhibits a low but significant activity. In the brain, tyramine N-acylation activity was heterogenously distributed. The arylamine N-acetyltransferase has been partially purified from both rat liver and brain, the two enzymes being quite similar with respect to their chromatographic properties, optimal pH requirement (pH 7.8), and their kinetic parameters. The product N-acetyltyramine is not oxidized by liver amidohydrolase or monoamine oxidase.

Related Compounds

  • N-Acetyltyramine

Related Articles:

Selective nanomolar detection of dopamine using a boron-doped diamond electrode modified with an electropolymerized sulfobutylether-beta-cyclodextrin-doped poly(N-acetyltyramine) and polypyrrole composite film.

2009-05-15

[Anal. Chem. 81(10) , 4089-98, (2009)]

Mechanistic and structural analysis of Drosophila melanogaster arylalkylamine N-acetyltransferases.

2014-12-16

[Biochemistry 53(49) , 7777-93, (2014)]

Effect of acetyl derivatives of some sympathomimetic amines on the blood pressure of the rat.

1977-02-01

[Acta Pharmacol. Toxicol. (Copenh.) 40(2) , 247-58, (1977)]

Partial purification and properties of N-acetylhistamine deacetylase.

1976-07-08

[Biochim. Biophys. Acta 438(2) , 532-9, (1976)]

Effect of spores of saprophytic fungi on phytoalexin accumulation in seeds of frog-eye leaf spot and stem canker-resistant and -susceptible soybean (Glycine max L.) cultivars.

2000-08-01

[J. Agric. Food Chem. 48(8) , 3662-5, (2000)]

More Articles...