Process improvements for the preparation of kilo quantities of a series of isoindoline compounds

TJ Watson, TA Ayers, N Shah, D Wenstrup…

Index: Organic Process Research and Development, , vol. 7, # 4 p. 521 - 532

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Citation Number: 27

Abstract

... Organic Process Research & Development. ... to obtain a high yield of intermediate 8, as exposure of chloroimidates to catalytic organic bases will ... The reduction process developed for HMR 2934 (1) worked even more efficiently in this case, because unsubstituted isoindoline 34 ...

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