Tetrahedron

Synthesis of Amaryllidaceae alkaloids, siculine, oxocrinine, epicrinine, and buflavine

S Kodama, H Takita, T Kajimoto, K Nishide, M Node

Index: Kodama, Sumiaki; Takita, Hirofumi; Kajimoto, Tetsuya; Nishide, Kiyoharu; Node, Manabu Tetrahedron, 2004 , vol. 60, # 22 p. 4901 - 4907

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Citation Number: 35

Abstract

Three crinane type of alkaloids isolated from Amaryllidaceae family were synthesized by taking advantage of the PIFA-mediated intramolecular pp′ diphenol coupling reaction of norbelladine derivatives. Furthermore, buflavine was also prepared by using the pp′ diphenol coupling followed by dienone–phenol rearrangement as a key step.