Synthesis

Silver Acetate Mediated Acetoxylations of Alkyl Halides

R Nolla-Saltiel, UA Carrillo-Arcos, S Porcel

Index: Nolla-Saltiel, Roberto; Carrillo-Arcos, Ulises Alonso; Porcel, Susana Synthesis (Germany), 2014 , vol. 46, # 2 p. 165 - 169

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Abstract

Abstract Silver acetate promotes the acetoxylation of alkyl halides under neutral reaction conditions. The reaction is applicable to primary and activated secondary alkyl halides, and 2, 2-dibromoacetophenones for preparing the corresponding acetates in good yields. The presence of ester, amide, nitrile, hydroxy, and OTBDMS functions on the substrate is tolerated.

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