Pulmonary Pharmacology & Therapeutics 2014-06-01

Prostaglandin E2elicits greater bronchodilation than salbutamol in mouse intrapulmonary airways in lung slices

M. FitzPatrick, C. Donovan, J.E. Bourke

Index: Pulm. Pharmacol. Ther. 28(1) , 68-76, (2014)

Full Text: HTML

Abstract

Background Current asthma therapy may not adequately target contraction of smaller intrapulmonary airways, which are a major site of airway obstruction and inflammation. The aim of this study was to characterise responses of mouse intrapulmonary airways to prostaglandin E2 (PGE2) and compare its dilator efficacy with the β2-adrenoceptor agonist salbutamol in situ, using lung slices.

Related Compounds

  • Salbutamol
  • Dimethyl sulfoxide
  • Caffeine
  • Dinoprostone
  • HEPES
  • Ryanodine
  • AH 6809
  • Steptomycin sulfat...
  • SEROTONIN CR...
  • Serotonin hydrogen...

Related Articles:

Stereoselective inhibition of human butyrylcholinesterase by the enantiomers of bambuterol and their intermediates.

2015-03-01

[Drug Metab. Dispos. 43(3) , 344-52, (2015)]

Complementary usage of Rhodiola crenulata (L.) in chronic obstructive pulmonary disease patients: the effects on cytokines and T cells.

2015-04-01

[Phytother Res. 29(4) , 518-25, (2015)]

In vitro performance of spacers for aerosol delivery during adult mechanical ventilation.

2015-04-01

[J. Aerosol Med. Pulm. Drug Deliv. 28(2) , 130-6, (2015)]

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

2010-01-01

[Chem. Res. Toxicol. 23 , 171-83, (2010)]

Revival of physostigmine - a novel HPLC assay for simultaneous determination of physostigmine and its metabolite eseroline designed for a pharmacokinetic study of septic patients.

2015-07-01

[Clin. Chem. Lab Med. 53 , 1259-64, (2015)]

More Articles...