Palladium??Mediated Fluorination of Arylboronic Acids

T Furuya, HM Kaiser, T Ritter

Index: Furuya, Takeru; Kaiser, Hanns Martin; Ritter, Tobias Angewandte Chemie - International Edition, 2008 , vol. 47, # 32 p. 5993 - 5996

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Citation Number: 192

Abstract

Fluorinated organic molecules have become increasingly important as pharmaceuticals [1] and tracers for positronemission tomography (PET), a powerful technology for noninvasive molecular imaging.[2] The nucleus of choice for PET is fluorine-18 (18F), which is typically introduced into PET tracers through the formation of carbon–fluorine bonds using nucleophilic fluoride (18FÀ) under harsh reaction conditions.[3] The short half-life of 18F ( ...

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