Chemical Communications 2012-06-14

Highly efficient enantioselective three-component synthesis of 2-amino-4H-chromenes catalysed by chiral tertiary amine-thioureas.

Gaosheng Yang, Chongrong Luo, Xiaolong Mu, Tingting Wang, Xin-Yuan Liu

Index: Chem. Commun. (Camb.) 48(47) , 5880-2, (2012)

Full Text: HTML

Abstract

A three-component cascade reaction of salicylaldehyde, malononitrile/cyanoacetate and nitromethane catalysed by chiral tertiary amino-thioureas was developed, which leads to the production of highly functionalized 2-amino-4H-chromenes in good yields with good to excellent enantioselectivities.

Related Compounds

  • Malononitrile
  • nitromethane
  • Salicylaldehyde

Related Articles:

Synthesis of a novel 4H-pyran analog as minor groove binder to DNA using ethidium bromide as fluorescence probe.

2016-01-05

[Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 152 , 165-71, (2015)]

Design of donor-acceptor star-shaped oligomers for efficient solution-processible organic photovoltaics.

2014-01-01

[Faraday Discuss. 174 , 313-39, (2014)]

A facile synthesis of new monoazo disperse dyes derived from 4-hydroxyphenylazopyrazole-5-amines: evaluation of microwave assisted dyeing behavior.

2012-01-01

[Molecules 17(12) , 13891-909, (2012)]

Structure-activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors.

2015-05-01

[Bioorg. Med. Chem. 23(9) , 2024-34, (2015)]

Synthesis of 2-arylamino substituted 5,6-dihydropyrido[2,3-d]pyrimidine-7(8H)-ones from arylguanidines.

2012-11-01

[Mol. Divers. 16(4) , 639-49, (2012)]

More Articles...