Chemical Communications 2012-01-07

Suzuki-Miyaura coupling of heteroaryl boronic acids and vinyl chlorides.

Ashish Thakur, Kainan Zhang, Janis Louie

Index: Chem. Commun. (Camb.) 48(2) , 203-5, (2012)

Full Text: HTML

Abstract

A protocol for the Suzuki-Miyaura coupling of heteroaryl boronic acids and vinyl chlorides that minimizes protodeboronation is described. A combination of catalytic amounts of Pd(OAc)(2) and SPhos in conjunction with CsF in isopropanol effectively affords a variety of coupled products. Surprisingly, a dramatic temperature dependence in product selectivity was observed.This journal is © The Royal Society of Chemistry 2012

Related Compounds

  • Vinyl chloride

Related Articles:

Catalysis: The accelerator.

2013-03-14

[Nature 495(7440) , S10-1, (2013)]

Biodegradable surfactant stabilized nanoscale zero-valent iron for in situ treatment of vinyl chloride and 1,2-dichloroethane.

2012-04-15

[J. Hazard. Mater. 211-212 , 373-80, (2012)]

Considering pharmacokinetic and mechanistic information in cancer risk assessments for environmental contaminants: examples with vinyl chloride and trichloroethylene.

1995-07-01

[Chemosphere 31(1) , 2561-78, (1995)]

Vinyl chloride-a classical industrial toxicant of new interest.

2005-01-01

[Crit. Rev. Toxicol. 35(4) , 307-23, (2005)]

Iridium-catalyzed chemoselective and enantioselective hydrogenation of (1-chloro-1-alkenyl) boronic esters.

2012-01-23

[Angew. Chem. Int. Ed. Engl. 51(4) , 1014-8, (2012)]

More Articles...