Journal of Chromatography B 2007-12-01

Microemulsion electrokinetic chromatography for the separation of arctiin and arctigenin in Fructus Arctii and its herbal preparations.

Wenjuan Lü, Yonglei Chen, Yuxia Zhang, Xiuping Ding, Hongli Chen, Mancang Liu

Index: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 860(1) , 127-33, (2007)

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Abstract

A microemulsion electrokinetic chromatography method was used to separate arctiin and arctigenin in Fructus Arctii and its herbal preparations. The separation of arctiin and arctigenin was performed using a 1-butanol-SDS-ethyl acetate-water microemulsion in 10mM sodium tetraborate buffer. The analytes were baseline-resolved within 4 min. In the concentration range 5-500 microg/mL, the calibration curves reveal linear relationships between the peak area for each analyte and its concentration (correlation coefficients: 0.9993 for arctiin and 0.9998 for arctigenin). The method was applied to the analysis of arctiin and arctigenin in herbal preparations, and the recoveries were 98.7-103.1% for arctiin and 97.6-103.2% for arctigenin, respectively.

Related Compounds

  • Arctiin

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