Organic Letters 2011-03-18

Synthetic studies on indolocarbazoles: total synthesis of staurosporine aglycon.

Ganesan Gobi Rajeshwaran, Arasambattu K Mohanakrishnan

Index: Org. Lett. 13(6) , 1418-21, (2011)

Full Text: HTML

Abstract

A synthesis of staurosporine aglycon and its analogs was achieved in a 28-36% overall yield starting from 2-methylindole. The prominent key steps for the synthesis of the indolocarbazole alkaloids involved electrocyclization and nitrene insertion reactions.

Related Compounds

  • Zinc bromide
  • 2-Methylindole

Related Articles:

Asymmetric Rh-catalyzed intermolecular hydroacylation of 1,5-hexadiene with salicylaldehyde.

2009-10-01

[Chem. Pharm. Bull. 57(10) , 1158-60, (2009)]

Palladium-catalyzed cross-coupling of cyclopropylmagnesium bromide with aryl bromides mediated by zinc halide additives.

2010-10-01

[J. Org. Chem. 75(19) , 6677-80, (2010)]

Synthesis of tri- or tetrasubstituted pyrimidine derivatives through the [5+1] annulation of enamidines with either N,N-dimethylformamide dialkyl acetals or orthoesters and their application in a ring transformation of pyrimidines to pyrido[2,3-d]pyrimidin-5-one derivatives.

2011-08-16

[Chemistry 17(34) , 9385-94, (2011)]

Stereoselective glycosylations using benzoylated glucosyl halides with inexpensive promoters.

2008-06-09

[Carbohydr. Res. 343(8) , 1297-308, (2008)]

[Halogenated anesthetic vaporizers: importance of maintenance regulations].

1998-01-01

[Ann. Fr. Anesth. Reanim. 17(7) , 747-9, (1998)]

More Articles...