Archives of Dermatological Research 2012-12-01

Influence of certain ingredients on the SPF determined in vivo.

Céline Couteau, Catherine Chauvet, Eva Paparis, Laurence J M Coiffard

Index: Arch. Dermatol. Res. 304(10) , 817-21, (2012)

Full Text: HTML

Abstract

When determined in vitro, the SPF of certain commercial sunscreen products can be lower than the SPF indicated on the label. The study of the composition of this type of product enabled us to note that the majority contained substances reputed to have anti-inflammatory properties. This effect is shown by inhibiting the erythema, without protecting the skin, which constitutes a serious public health problem. The anti-inflammatory effects of αbisabolol-, allantoin- and 18-β-glycyrrhetinic acid-based emulsions, as well as commercial sun products containing any one of these molecules, have been tested with phorbol myristate acetate on mice. The effectiveness of these sunscreens products is quantified using two indicators: SPF (sun protection factor) and PF-UVA (protection factor-UVA) by in vitro method. We were thus able to show that certain sun products have an anti-inflammatory effect, which in turn causes the SPF value shown on the product to be overestimated, indeed sometimes by considerably large margins.

Related Compounds

  • levomenol
  • allantoin

Related Articles:

The antimicrobial activity of alpha-bisabolol and tea tree oil against Solobacterium moorei, a Gram-positive bacterium associated with halitosis.

2013-01-01

[Arch. Oral Biol. 58(1) , 10-6, (2013)]

Antitumor effects of α-bisabolol against pancreatic cancer.

2011-12-01

[Cancer Sci. 102(12) , 2199-205, (2011)]

In vitro and in vivo antimalarial activity of essential oils and chemical components from three medicinal plants found in northeastern Brazil.

2012-05-01

[Planta Med. 78(7) , 658-64, (2012)]

Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains.

2011-07-14

[Mutat. Res. 723(1) , 18-25, (2011)]

Enantioselective microbial synthesis of the indigenous natural product (-)-α-bisabolol by a sesquiterpene synthase from chamomile (Matricaria recutita).

2014-10-15

[Biochem. J. 463(2) , 239-48, (2014)]

More Articles...