New Journal of Chemistry

The chemical synthesis of phosphorothioate and phosphorodithioate analogues of lysophosphatidic acid (LPA) and cyclic phosphatidic acid (CPA)

P Rytczak, M Koziołkiewicz, A Okruszek

Index: Rytczak, Przemyslaw; Koziolkiewicz, Maria; Okruszek, Andrzej New Journal of Chemistry, 2010 , vol. 34, # 5 p. 1008 - 1017

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Citation Number: 8

Abstract

The chemical synthesis of new sulfur analogues of lysophospholipids has been described, including phosphorothioate/phosphorodithioate derivatives of lysophosphatidic acids (LPA) and phosphorothioate/phosphorodithioate derivatives of cyclic phosphatidic acids (cPA). For the preparation of LPA and cPA derivatives both oxathiaphospholane and dithiaphospholane approaches have been employed. Each lysophospholipid analogue ...

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