Ukrainskij biokhimicheskij zhurnal/Ukrayins'kij biokhimichnij zhurnal/Ukrainian biochemical journal 1987-01-01

[Effect of thiamine and its derivatives on acetylcholinesterase activity of the blood and brain of albino mice].

S A Petrov, A Ia Rozanov, D V Tishchenko

Index: Ukr. Biokhim. Zh. 59(3) , 76-9, (1987)

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Abstract

Thiamine, thiaminepyrophosphate and 4-methyl-5-beta-oxyethylthiazole are studied for their effect on the acetylcholinesterase activity in the brain, blood plasma and cells. The activity of acetylcholinesterase in blood cells is shown to be inhibited most of all by thiamine and thiazole. Acetylcholinesterase of the brain has been efficiently inhibited only by thiamine pyrophosphate.


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