Bulletin of Experimental Biology and Medicine 2011-09-01

Anxiolytic and antidepressant effects of aqueous tincture of the aerial part of Myosotis arvensis.

N Yu Polomeyeva, R V Gurto, O S Bryushinina, V A Slepichev, A V Kaigorodtsev, V Yu Smirnov, N I Suslov, V V Udut

Index: Bull. Exp. Biol. Med. 151(5) , 604-6, (2011)

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Abstract

Experiments on outbred albino mice showed a significant anxiolytic effect of aqueous tincture of the aerial part of Myosotis arvensis (L.) (Boraginaceae) in a single daily dose of 0.5 ml/kg. In a dose of 2 ml/kg, the tincture of M. arvensis aerial part exhibited an anxiolytic and antidepressant effect. In contrast to phenazepam, aqueous tincture of M. arvensis did not inhibit exploratory and motor activities.

Related Compounds

  • Phenazepam

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