Applied and Environmental Microbiology 2010-01-01

Aromatic hydroxylation of indan by o-xylene-degrading Rhodococcus sp. strain DK17.

Dockyu Kim, Choong Hwan Lee, Jung Nam Choi, Ki Young Choi, Gerben J Zylstra, Eungbin Kim

Index: Appl. Environ. Microbiol. 76(1) , 375-7, (2010)

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Abstract

The metabolically versatile Rhodococcus sp. strain DK17 utilizes indan as a growth substrate via the o-xylene pathway. Metabolite and reverse transcription-PCR analyses indicate that o-xylene dioxygenase hydroxylates indan at the 4,5 position of the aromatic moiety to form cis-indan-4,5-dihydrodiol, which is dehydrogenated to 4,5-indandiol by a dehydrogenase. 4,5-indandiol undergoes ring cleavage by a meta-cleavage dioxygenase.

Related Compounds

  • o-xylene
  • Dimethyl benzene
  • Indane

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