Molecules 2012-01-01

An ent-kaurane-type diterpene in Croton antisyphiliticus mart.

Sarazete Pereira, Silvia Taleb-Contini, Juliana Coppede, Paulo Pereira, Bianca Bertoni, Suzelei França, Ana Maria Pereira

Index: Molecules 17(8) , 8851-8, (2012)

Full Text: HTML

Abstract

Croton antisyphiliticus is a medicinal plant widely used in the treatment of microbial infections, especially those affecting the genital tract. Crude extract, fractions and pure compound isolated from roots of this species were investigated to validate their antimicrobial activity against Escherichia coli and Staphylococcus aureus. The compound ent-kaur-16-en-18-oic acid was isolated as a major component (0.7% of crude extract), and its MIC value determined against S. aureus (ATCC 6538) was 250 μg/mL. This is the first phytochemical work on the species monitored with antimicrobial assay.

Related Compounds

  • Kaurenoic acid

Related Articles:

Development and validation of two methods based on high-performance liquid chromatography-tandem mass spectrometry for determining 1,2-benzopyrone, dihydrocoumarin, o-coumaric acid, syringaldehyde and kaurenoic acid in guaco extracts and pharmaceutical preparations.

2011-04-01

[J. Sep. Sci. 34(7) , 740-8, (2011)]

Anticonvulsant effect of kaurenoic acid isolated from the root bark of Annona senegalensis.

2013-08-01

[Pharmacol. Biochem. Behav. 109 , 38-43, (2013)]

Biosynthesis of uterotonic diterpenes from Montanoa tomentosa (zoapatle).

2009-12-15

[J. Plant Physiol. 166(18) , 1961-7, (2009)]

Isolation of two bioactive diterpenic acids from Copaifera glycycarpa oleoresin by high-speed counter-current chromatography.

2010-01-01

[Phytochem. Anal. 21(6) , 539-43, (2010)]

Hypoglycaemic effects of tea extracts and ent-kaurenoic acid from Smallanthus sonchifolius.

2010-11-01

[Nat. Prod. Res. 24(18) , 1771-82, (2010)]

More Articles...