Organic Letters 2013-09-06

Rh(III)-catalyzed tandem C-H allylation and oxidative cyclization of anilides: a new entry to indoles.

Ana Cajaraville, Susana López, Jesús A Varela, Carlos Saá

Index: Org. Lett. 15(17) , 4576-9, (2013)

Full Text: HTML

Abstract

Rh(III)-catalyzed tandem C-H allylation and oxidative cyclization of anilides with allyl carbonates in the presence of a slight excess of AgSbF6 salt and Cu(OAc)2 as oxidant affords easy, economical access to important bioactive 2-methylindoles. The new reaction supports a wide range of functional groups on the anilide substrate. A possible mechanism is proposed as a basis for its rational further development.

Related Compounds

  • Rhodium
  • 2-Methylindole

Related Articles:

Toxic impact of bromide and iodide on drinking water disinfected with chlorine or chloramines.

2014-10-21

[Environ. Sci. Technol. 48(20) , 12362-9, (2014)]

Synthesis and Temperature-Induced Structural Phase and Spin Transitions in Hexadecylboron-Capped Cobalt(II) Hexachloroclathrochelate and Its Diamagnetic Iron(II)-Encapsulating Analogue.

2015-06-15

[Inorg. Chem. 54 , 5827-38, (2015)]

Bio-inspired catalytic imine reduction by rhodium complexes with tethered Hantzsch pyridinium groups: evidence for direct hydride transfer from dihydropyridine to metal-activated substrate.

2013-03-18

[Angew. Chem. Int. Ed. Engl. 52(12) , 3411-6, (2013)]

Lead exposure causes thyroid abnormalities in diabetic rats.

2015-01-01

[Int. J. Clin. Exp. Med. 8 , 7160-7, (2015)]

Gravimetric preparation and characterization of primary reference solutions of molybdenum and rhodium.

2015-04-01

[Anal. Bioanal. Chem 407(11) , 3093-102, (2015)]

More Articles...