A practical and convenient synthesis of hotrienol, an excellent fruity smelling compound.
Yoshifumi Yuasa, Yasushi Kato
Index: J. Agric. Food Chem. 51(14) , 4036-9, (2003)
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Abstract
The practical and convenient synthesis of hotrienol, which is an excellent fruity smelling compound, has been performed by the ene-type chlorination of linalyl acetate and then dehydrochlorinated by lithium bromide and lithium carbonate in DMF, followed by hydrolysis in three steps with an overall yield of 55%.
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