Mini-Reviews in Medicinal Chemistry 2006-01-01

Solid-phase synthesis in the twenty-first century.

A Ganesan

Index: Mini Rev. Med. Chem. 6(1) , 3-10, (2006)

Full Text: HTML

Abstract

Solid-phase synthesis is a powerful tool for achieving high-throughput chemistry. This review discusses recent diverse examples from my group: the solid-phase synthesis of unsymmetrical guanidines, polymer-supported versions of cyclooctadiene and 9-BBN, a triflate-like linker, the synthesis of tetrahydro-beta-carbolines by the acyliminium Pictet-Spengler reaction, and a total synthesis of the antimycobacterial cyclic depsipeptide natural product kahalalide A.

Related Compounds

  • 9-Borabicyclo[3.3....

Related Articles:

Spectroscopic and microscopic investigation of gold nanoparticle formation: ligand and temperature effects on rate and particle size.

2011-06-01

[J. Am. Chem. Soc. 133(21) , 8179-90, (2011)]

Synthesis of aryl/alkyl building blocks for dendrimer and hyperbranched polymer synthesis.

2004-03-04

[Org. Lett. 6 , 667-669, (2004)]

Multicomponent Mannich reactions with boron enolates derived from diazo esters and 9-BBN.

2011-05-06

[Org. Lett. 13 , 2510, (2011)]

PS-COD and PS-9-BBN: polymer-supported reagents for solution-phase parallel synthesis.

2005-03-03

[Org. Lett. 7(5) , 831-3, (2005)]

[Chem. Lett. 33 , 396-397, (2004)]

More Articles...