Synthesis of quinolin-2-one alkaloid derivatives and their inhibitory activities against HIV-1 reverse transcriptase

P Cheng, Q Gu, W Liu, JF Zou, YY Ou, ZY Luo, JG Zeng

Index: Molecules, , vol. 16, # 9 p. 7649 - 7661

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Citation Number: 11

Abstract

... The coordinates of the RT-wfavirenz complex (PDB code: 1FK9) [12,18] were downloaded, and the molecular structure of the most potent ... The carboxamide group of the molecule interacts with the main-chain of Lys101 by hydrogen bond interactions. ... Molecules 2011, 16 7654 ...