Journal of Zoo and Wildlife Medicine 2014-12-01

Valvular dysplasia and congestive heart failure in a juvenile African penguin (Spheniscus demersus).

Allyson McNaughton, Salvatore Frasca, Neha Mishra, Allison D Tuttle

Index: J. Zoo Wildl. Med. 45(4) , 987-90, (2014)

Full Text: HTML

Abstract

Abstract: An aquarium-housed, 6-mo-old African penguin (Spheniscus demersus) presented with acute respiratory distress. Auscultation revealed a grade II-III systolic murmur in the absence of adventitial sounds, and an enlarged heart without pulmonary edema was seen radiographically. Echocardiographic evaluation revealed atrioventricular (AV) valvular dysplasia and ventricular enlargement. The penguin was treated with enalapril, furosemide, and pimobendan but died within 3 wk of detection of the murmur. Congenital dysplasia of the right AV valve with right atrial and ventricular dilation and ventricular hypertrophy were diagnosed on postmortem examination.

Related Compounds

  • Furosemide
  • Enalapril maleate
  • Pimobendan
  • Enalapril

Related Articles:

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

2010-01-01

[Chem. Res. Toxicol. 23 , 171-83, (2010)]

Revival of physostigmine - a novel HPLC assay for simultaneous determination of physostigmine and its metabolite eseroline designed for a pharmacokinetic study of septic patients.

2015-07-01

[Clin. Chem. Lab Med. 53 , 1259-64, (2015)]

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

2011-12-01

[J. Sci. Ind. Res. 65(10) , 808, (2006)]

Convenient QSAR model for predicting the complexation of structurally diverse compounds with β-cyclodextrins

2009-01-01

[Bioorg. Med. Chem. 17 , 896-904, (2009)]

The Japanese toxicogenomics project: application of toxicogenomics.

2010-02-01

[Mol. Nutr. Food. Res. 54 , 218-27, (2010)]

More Articles...