Synthesis, X-Ray Crystallography, and Reactions of N-Acyl and N-Carbamoyl Succinimides

CA Goodman, JB Eagles, L Rudahindwa…

Index: Goodman, Cassie A.; Eagles, Joel B.; Rudahindwa, Leandre; Hamaker, Christopher G.; Hitchcock, Shawn R. Synthetic Communications, 2013 , vol. 43, # 16 p. 2155 - 2164

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Citation Number: 5

Abstract

A collection of N-acyl and N-carbamoyl succinimides were prepared by acylation of succinimide with acyl chlorides or by ethylene dichloride (EDC) coupling of carboxylic acids. The x-ray crystal structures of N-benzoyl and N-p-nitrobenzoyl succinimides were determined. The N-acyl succinimides were effective in acylating primary amines, a secondary amine, and an aromatic amine. ... Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic ...

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