CNS Spectrums 2013-12-01

Role of α1 adrenergic antagonism in the mechanism of action of iloperidone: reducing extrapyramidal symptoms.

Stephen M Stahl

Index: CNS Spectr. 18(6) , 285-8, (2013)

Full Text: HTML

Abstract

The low incidence of extrapyramidal side effects associated with the atypical antipsychotic iloperidone may be linked to its unique binding profile of high affinity antagonism of both α1 adrenergic receptors and serotonin 2A receptors.

Related Compounds

  • Dopamine hydrochlo...
  • Iloperidone

Related Articles:

'Dopamine-first' mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile.

2015-03-01

[FEBS J. 282(6) , 1137-51, (2015)]

Permeation of Dopamine Sulfate through the Blood-Brain Barrier.

2015-01-01

[PLoS ONE 10 , e0133904, (2015)]

Increasing the Collision Rate of Particle Impact Electroanalysis with Magnetically Guided Pt-Decorated Iron Oxide Nanoparticles.

2015-07-28

[ACS Nano 9 , 7583-95, (2015)]

Force nanoscopy of hydrophobic interactions in the fungal pathogen Candida glabrata.

2015-02-24

[ACS Nano 9(2) , 1648-55, (2015)]

A simple method for patterning poly(dimethylsiloxane) barriers in paper using contact-printing with low-cost rubber stamps.

2015-02-09

[Anal. Chim. Acta 858 , 82-90, (2015)]

More Articles...