Superparamagnetic nanoparticle-supported enzymatic resolution of racemic carboxylates.
Hari M R Gardimalla, Deendayal Mandal, Philip D Stevens, Max Yen, Yong Gao
Index: Chem. Commun. (Camb.) (35) , 4432-4, (2005)
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Abstract
Candida rugosa lipase immobilized on maghemite nanoparticles demonstrated high stereoselectivity in kinetic resolution of racemic carboxylates and improved long-term stability over its parent free enzyme, allowing the supported enzyme to be repeatedly used for a series of chiral resolution reactions.
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