Tetrahedron

A simple method for synthesis of amides and peptides through acyl chlorides: A rapid synthesis of thyrotropin releasing hormone

F Matsuda, S Itoh, N Hattori, M Yanagiya, T Matsumoto

Index: Matsuda, Fuyuhiko; Itoh, Shin; Hattori, Noritaka; Yanagiya, Mitsutoshi; Matsumoto, Takeshi Tetrahedron, 1985 , vol. 41, # 18 p. 3625 - 3631

Full Text: HTML

Citation Number: 33

Abstract

By improvement of the classical SOCl2-pyridine method for the preparation of acid chlorides, amides and optically pure peptides were synthesized rapidly in a simple manner from DCHA dicyclohexylammonium) salts of carboxylic acids. This modified SOCl2-pyridine method was applied to a rapid synthesis of TRH.

Related Articles:

Hexabromoacetone as tribromoacetylating agent of alcohols and amines and as mediator in the conversion of carboxylic acids into amides in the presence of …

[Menezes, Fabricio G.; Kolling, Rosane; Bortoluzzi, Adailton J.; Gallardo, Hugo; Zucco, Cesar Tetrahedron Letters, 2009 , vol. 50, # 21 p. 2559 - 2561]

Group IV-Metal-Catalyzed Aminolysis of N-Acyl-2-oxazolidinones: Applications to the Chemoselective and Enantioselective Carbonylation of Primary Alkylamines

[Yokomatsu, Tsutomu; Arakawa, Akio; Shibuya, Shiroshi Journal of Organic Chemistry, 1994 , vol. 59, # 12 p. 3506 - 3508]

Group IV-Metal-Catalyzed Aminolysis of N-Acyl-2-oxazolidinones: Applications to the Chemoselective and Enantioselective Carbonylation of Primary Alkylamines

[Yokomatsu, Tsutomu; Arakawa, Akio; Shibuya, Shiroshi Journal of Organic Chemistry, 1994 , vol. 59, # 12 p. 3506 - 3508]

Synthesis, X-Ray Crystallography, and Reactions of N-Acyl and N-Carbamoyl Succinimides

[Goodman, Cassie A.; Eagles, Joel B.; Rudahindwa, Leandre; Hamaker, Christopher G.; Hitchcock, Shawn R. Synthetic Communications, 2013 , vol. 43, # 16 p. 2155 - 2164]

Alkylation of nitriles with gaseous carbenium ions. The Ritter reaction in the dilute gas state

[Cacace, Fulvio; Ciranni, Giovanna; Giacomello, Pierluigi Journal of the American Chemical Society, 1982 , vol. 104, # 8 p. 2258 - 2261]

More Articles...