Mild and Efficient Copper??Catalyzed Cyanation of Aryl Iodides and Bromides

…, A Ouali, JF Spindler, M Taillefer

Index: Cristau, Henri-Jean; Ouali, Armelle; Spindler, Jean-Francis; Taillefer, Marc Chemistry - A European Journal, 2005 , vol. 11, # 8 p. 2483 - 2492

Full Text: HTML

Citation Number: 151

Abstract

Abstract An efficient copper-catalyzed cyanation of aryl iodides and bromides is reported. Our system combines catalytic amounts of both copper salts and chelating ligands. The latter, which have potential nitrogen-and/or oxygen-binding sites, have never previously been used in this type of reaction. A protocol has been developed that enables the cyanation of aryl bromides through the copper-catalyzed in situ production of the ...

Related Articles:

A Simple Synthesis of Nitriles from Aldoximes (1)

[Coskun, Necdet Synthetic Communications, 2004 , vol. 34, # 9 p. 1625 - 1630]

Room Temperature Aerobic Oxidation of Amines by a Nanocrystalline Ruthenium Oxide Pyrochlore Nafion Composite Catalyst

[Venkatesan, Shanmuganathan; Kumar, Annamalai Senthil; Lee, Jyh-Fu; Chan, Ting-Shan; Zen, Jyh-Myng Chemistry - A European Journal, 2012 , vol. 18, # 20 p. 6147 - 6151]

Facile transformation of esters to nitriles

[Suzuki, Yusuke; Moriyama, Katsuhiko; Togo, Hideo Tetrahedron, 2011 , vol. 67, # 41 p. 7956 - 7962]

One-pot conversion of aromatic bromides and aromatics into aromatic nitriles via aryllithiums and their DMF adduct

[Ushijima, Sousuke; Moriyama, Katsuhiko; Togo, Hideo Tetrahedron, 2011 , vol. 67, # 5 p. 958 - 964]

Direct transformation of N, N-disubstituted amides and isopropyl esters to nitriles

[Suzuki, Yusuke; Yoshino, Takumi; Moriyama, Katsuhiko; Togo, Hideo Tetrahedron, 2011 , vol. 67, # 21 p. 3809 - 3814]

More Articles...