Bioorganic & Medicinal Chemistry 2010-01-01

Biflavonoids fromTorreya nuciferadisplaying SARS-CoV 3CLproinhibition

Young Bae Ryu, Hyung Jae Jeong, Jang Hoon Kim, Young Min Kim, Ji-Young Park, Doman Kim, Thi Thanh Hanh Naguyen, Su-Jin Park, Jong Sun Chang, Ki Hun Park, Mun-Chual Rho, Woo Song Lee, Young Bae Ryu, Hyung Jae Jeong, Jang Hoon Kim, Young Min Kim, Ji-Young Park, Doman Kim, Thi Thanh Hanh Naguyen, Su-Jin Park, Jong Sun Chang, Ki Hun Park, Mun-Chual Rho, Woo Song Lee

Index: Bioorg. Med. Chem. 18 , 7940-7, (2010)

Full Text: HTML

Abstract

Inhibitory activity appeared to be associated with the presence of an apigenin moiety at position C-3′ of flavones, as biflavonoid had an effect on SARS-CoV 3CL pro inhibitory activity.

Related Compounds

  • Apigenin
  • Luteolin
  • amentoflavone

Related Articles:

Rapid evaluation and comparison of natural products and antioxidant activity in calendula, feverfew, and German chamomile extracts.

2015-03-13

[J. Chromatogr. A. 1385 , 103-10, (2015)]

Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts.

2015-08-15

[Biochem. Pharmacol. 96 , 337-48, (2015)]

Apigenin induces caspase-dependent apoptosis by inhibiting signal transducer and activator of transcription 3 signaling in HER2-overexpressing SKBR3 breast cancer cells.

2015-08-01

[Mol. Med. Report. 12 , 2977-84, (2015)]

Membrane transport of nobilin conjugation products and use of the extract of Chamomillae romanae flos influence absorption of nobilin in the Caco-2 model.

2015-04-05

[Eur. J. Pharm. Sci. 70 , 92-106, (2015)]

Differential metabolomic analysis of the potential antiproliferative mechanism of olive leaf extract on the JIMT-1 breast cancer cell line.

2015-02-01

[J. Pharm. Biomed. Anal. 105 , 156-62, (2015)]

More Articles...