Synthesis of a branched glycopeptide derivative containing terminal D-mannose 6-phosphate residues.

Y Ichikawa, Y C Lee

Index: Carbohydr. Res. 198 , 235, (1990)

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Abstract

A branched glycopeptide derivative incorporating two D-mannose 6-phosphate residues was prepared by coupling 6-aminohexyl 6-O-[bis(2,2,2-trichloroethoxy)phosphinyl]-alpha-D-mannopyranoside with N-acetyl-L-tyrosyl-L-aspart-oyldi-L-alanine followed by reductive deprotection of the phosphate group.