Antimicrobial Agents and Chemotherapy 2007-07-01

gyrA and parC Mutations and associated quinolone resistance in Vibrio anguillarum serotype O2b strains isolated from farmed Atlantic cod (Gadus morhua) in Norway.

D J Colquhoun, L Aarflot, C F Melvold

Index: Antimicrob. Agents Chemother. 51 , 2597-9, (2007)

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Abstract

MIC testing of Vibrio anguillarum isolates recovered from diseased farmed Atlantic cod revealed oxolinic acid MICs of < or =0.001, 0.06, and 16 microg ml(-1). Single gyrA Ser-Ile substitutions were identified at position 83 of the intermediate and resistant strains, while a parC Ser-Leu substitution at position 85 was found only in the resistant strain.

Related Compounds

  • Nalidixic acid
  • Enrofloxacin
  • oxolinic acid
  • Flumequine

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