Synlett

A Practical and Highly Chemoselective Hydrogenation of Aldehydes with a Copper Catalyst

H Shimizu, N Sayo, T Saito

Index: Shimizu, Hideo; Sayo, Noboru; Saito, Takao Synlett, 2009 , # 8 p. 1295 - 1298

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Citation Number: 12

Abstract

Abstract A practical hydrogenation of aldehydes mediated by an inexpensive and easily available base metal, copper, is reported. A copper complex associated with 1, 4-bis (diphenylphosphino) butane (DPPB) hydrogenates α, β-unsaturated aldehydes in a highly chemoselective fashion to give allylic alcohols with improved catalytic productivities. The reaction system was also effective for the conversion of simple aldehydes to the ...