Electroretinographic study during acute Aramite intoxication of the white mouse.

Senda Mezghani Maalej, Faouzia Mahjoubi Rhimi, Marguerite Fines, Basma Mnif, Roland Leclercq, Adnene Hammami

Index: Toxicol. Eur. Res. 2(4) , 195-8, (1979)

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Abstract

Aramite was injected to white mice and the electroretinograms recorded in response to electronic flashes. The following phenomena were remarked: a more and more important flattening of a-waves; a simultaneous collapse of b-waves; a more and more delayed return of a-waves to the isoelectric line; vanishing c-waves. Those actions were explained by an intoxication of the photoreceptors by Aramite and by a resulting difficulty of the photoreceptors to stimulate bipolar cells.