Synthesis, in??vitro Antimicrobial and Cytotoxic Studies of Novel Azetidinone Derivatives
RS Keri, KM Hosamani, HS Reddy…
Index: Harisha, Reddy S.; Hosamani, Kallappa M.; Keri, Rangappa S. Archiv der Pharmazie, 2009 , vol. 342, # 7 p. 412 - 419
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Citation Number: 12
Abstract
Abstract Developing novel antimicrobial drugs is increasingly important in the modern pharmaceutical industry. A series of novel 3-chloro-4-[4-(2-oxo-2H-chromen-4-ylmethoxy) phenyl]-1-phenylazetidin-2-ones 5a–o have been synthesized from 4- bromomethylcoumarins 1a–e and 4-aryliminomethyl-phenols 3a–c. These compounds were screened for their in-vitro antibacterial activity against two Gram-positive (Staphylococcus ...
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