Versatile and efficient synthesis of a new class of aza-based phosphinic amide ligands via unusual PC cleavage

SC Tsai, YS Fu, JH Liao, SJ Yu

Index: Tsai, Shih-Chung; Fu, Yaw-Shien; Liao, Ju-Hsiou; Yu, Shuchun Joyce Helvetica Chimica Acta, 2006 , vol. 89, # 12 p. 3007 - 3017

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Citation Number: 7

Abstract

A new class of bidentate, aza-based phosphinic amide ligands of the type RN (H) P (= O)(2- py) 2 (2-py= 2-pyridyl) was synthesized within minutes via a one-pot process including Staudinger reaction of an organic azide (RN3) with 2-pyridylphosphines, followed by partial, unprecedented hydrolysis under loss of one aromatic substituent. The structure of the unusual-hydrolysis product H2C= CH (CH2) 9-N (H) P (= O)(2-py) 2 (5a) was ...