Ion mobility spectrometry for detection of skin volatiles.

Veronika Ruzsanyi, Pawel Mochalski, Alex Schmid, Helmut Wiesenhofer, Martin Klieber, Hartmann Hinterhuber, Anton Amann

Index: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 911 , 84-92, (2012)

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Abstract

Volatile organic compounds (VOCs) released by humans through their skin were investigated in near real time using ion mobility spectrometry after gas chromatographic separation with a short multi-capillary column. VOCs typically found in a small nitrogen flow covering the skin are 3-methyl-2-butenal, 6-methylhept-5-en-2-one, sec-butyl acetate, benzaldehyde, octanal, 2-ethylhexanol, nonanal and decanal at volume fractions in the low part per billion-(ppb) range. The technique presented here may contribute to elucidating some physiological processes occurring in the human skin.Copyright © 2012 Elsevier B.V. All rights reserved.