Organic & Biomolecular Chemistry 2012-06-21

Multi-component anion relay cascade of 1-acetylcyclopropanecarboxamides, aldehydes and acrylonitrile: access to biscyanoethylated furo[3,2-c]pyridinones.

Shaoxia Lin, Ying Wei, Fushun Liang, Baozhong Zhao, Yanling Liu, Pengjun Liu

Index: Org. Biomol. Chem. 10(23) , 4571-6, (2012)

Full Text: HTML

Abstract

A highly efficient multi-component anion relay cascade reaction based on 1-acetylcyclopropanecarboxamides, aldehydes and acrylonitrile has been developed, which provides strategically novel and atom-economic access to biologically important biscyanoethylated furo[3,2-c]pyridinones. In this one-pot transformation, up to five bonds (one C-N, one C-O and three C-C bonds) were constructed.

Related Compounds

  • Acrylonitrile
  • 2-pyridone

Related Articles:

Self-cleaning Metal Organic Framework (MOF) based ultra filtration membranes--a solution to bio-fouling in membrane separation processes.

2014-01-01

[Sci. Rep. 4 , 6555, (2014)]

Aptamer-functionalized solid phase microextraction-liquid chromatography/tandem mass spectrometry for selective enrichment and determination of thrombin.

2014-10-03

[Anal. Chim. Acta 845 , 45-52, (2014)]

Double salts of ionic-liquid-based surfactants in microextraction: application of their mixed hemimicelles as novel sorbents in magnetic-assisted micro-dispersive solid-phase extraction for the determination of phenols.

2015-11-01

[Anal. Bioanal. Chem 407 , 8753-64, (2015)]

Toxicological assessment of kretek cigarettes: Part 1: background, assessment approach, and summary of findings.

2014-12-01

[Regul Toxicol Pharmacol 70 Suppl 1 , S2-14, (2014)]

Surface-engineered dendrimeric nanoconjugates for macrophage-targeted delivery of amphotericin B: formulation development and in vitro and in vivo evaluation.

2015-05-01

[Antimicrob. Agents Chemother. 59 , 2479-87, (2015)]

More Articles...