P2O5SiO2: A Simple and Effective Catalyst for the Synthesis of Nsubstituted 1-Alkyl and 1-Aryl 3-Aminoisoquinolines

LJ Mendez, AS Canepa, R Rimada…

Index: Mendez, Leticia J.; Canepa, Alicia S.; Rimada, Ruben; Bravo, Rodolfo D. Letters in Organic Chemistry, 2013 , vol. 10, # 4 p. 240 - 244

Full Text: HTML

Citation Number: 0

Abstract

A synthesis of N-substituted 1-alkyl and 1-aryl 3-aminoisoquinolines by cyclocondensation of 2-acylphenylacetonitriles with aliphatic and aromatic amines using P2O5/SiO2 as catalysts is described. Selectivity, simplicity of operation and easy work-up are some advantages of this method.

Related Articles:

Photochemical preparation of highly functionalized 1-indanones

[Wessig, Pablo; Glombitza, Clemens; Mueller, Gunnar; Teubner, Janek Journal of Organic Chemistry, 2004 , vol. 69, # 22 p. 7582 - 7591]

Microwave??Assisted One??Step Synthesis of Acetophenones via Palladium??Catalyzed Regioselective Arylation of Vinyloxytrimethylsilane

[Qian, Wangke; Zhang, Lei; Sun, Haifeng; Jiang, Hualiang; Liu, Hong Advanced Synthesis and Catalysis, 2012 , vol. 354, # 17 p. 3231 - 3236]

Photolysis of. alpha.-peracetoxynitriles. 2. A comparison of two synthetic approaches to 18-cyano-20-ketosteroids

[Freerksen; Pabst; Raggio; Sherman; Wroble; Watt Journal of the American Chemical Society, 1977 , vol. 99, # 5 p. 1536 - 1542]

Photochemical preparation of highly functionalized 1-indanones

[Wessig, Pablo; Glombitza, Clemens; Mueller, Gunnar; Teubner, Janek Journal of Organic Chemistry, 2004 , vol. 69, # 22 p. 7582 - 7591]

Photochemical preparation of highly functionalized 1-indanones

[Wessig, Pablo; Glombitza, Clemens; Mueller, Gunnar; Teubner, Janek Journal of Organic Chemistry, 2004 , vol. 69, # 22 p. 7582 - 7591]

More Articles...